Maryville athletic teams are known as the Saints .  The university competes at the NCAA Division II level in the Great Lakes Valley Conference (GLVC). Maryville was accepted into the GLVC for the 2009–10 school year, when the school began the transition to NCAA Division II athletics. Maryville became an active member of Division II in July 2011.  The Saints had formerly competed in the St. Louis Intercollegiate Athletic Conference , a Division III conference , since 1989 and had competed in Division III sports since 1978.